Alexander County
- Cairo, Cairo Bridge, spanning Ohio River (HAER IL-36)
- Cairo, Illinois National Guard Armory, 410 Washington Avenue (covenant)
- Cairo, Isabella Maud Rittenhouse House, 703 Walnut Street (covenant, EXPIRED)
- Cairo, Peter T. Langan House (HABS IL-218)
- Cairo, Store Building, 509 Commercial Avenue (HABS IL-25-21)
- Fayville, Keating House, U.S. Highway 430 (HABS IL-165)
- Gale vicinity, Old Route 3 Bridge over Miller Creek (HIER AX-2022-1)
- Thebes, Thebes Courthouse (HABS IL-25-17)